Migraine: Part I

Migraine genetics--a review: Part I.

Significant progress in molecular genetics has advanced our understanding of the genetic basis of migraine. The fundamentals of molecular genetics, and the recent advances in the field, are important for clinicians to understand, as they provide a foundation for critical appraisal of the literature, unprecedented insights into the pathogenesis of the disorder, and reveal promising treatment tar...

Migraine genetics: Part II.

Migraine clusters in families and is considered to be a strongly heritable disorder. Hemiplegic migraine is a rare subtype of migraine with aura that may occur as a familial or a sporadic condition. Three genes have been identified studying families with familial hemiplegic migraine (FHM). The first FHM gene that was identified is CACNA1A. A second gene, FHM2, has been mapped to chromosome 1 q ...

Childhood maltreatment and migraine (part I). Prevalence and adult revictimization: a multicenter headache clinic survey.

OBJECTIVES To examine the prevalence of childhood maltreatment and adult revictimization in migraineurs and the association with sociodemographic factors, depression and anxiety. BACKGROUND Population and practice-based studies have demonstrated an association of childhood abuse and headache in adults, although further details on headache diagnoses, characteristics, and comorbid conditions ar...

Part] I I

Part I : Part Ii : Part Iii : Part Iv

The theory of stick-slip is developed, based on the concept of a static and dynamic coefficient of friction. The dynamic coefficient is assumed to be independent of displacement and to depend wholly on normal stress across the surface. It is also assumed to be velocity-independent. The theory predicts that the stress drop during stick-slip is independent of machine stiffness. The displacement d...